Unique ID issued by UMIN | UMIN000014841 |
---|---|
Receipt number | R000017247 |
Scientific Title | Comparison of the effectiveness of celecoxib and loxoprofen sodium for postoperative pain in orthopedic patients |
Date of disclosure of the study information | 2014/08/18 |
Last modified on | 2015/07/11 00:11:57 |
Comparison of the effectiveness of celecoxib and loxoprofen sodium for postoperative pain in orthopedic patients
Comparison of the analgesic effect for orthopaedic postoperative pain
Comparison of the effectiveness of celecoxib and loxoprofen sodium for postoperative pain in orthopedic patients
Comparison of the analgesic effect for orthopaedic postoperative pain
Japan |
patients who were undergone orthopaedic surgery
Orthopedics |
Others
NO
To analyze the efficacy and safety of celecoxib and loxoprofen in postoperative pain after orthopaedic surgery
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
Numeric rating scale
Occurrence of side effect
Parallel
Randomized
Individual
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
YES
Numbered container method
2
Treatment
Medicine |
Take cerecoxib (100mg) 2 tablets a day
Take loxoprofen sodium (60mg) 3 tablets a day
20 | years-old | <= |
Not applicable |
Male and Female
Patients who can take celecoxib or loxoprofen sodium for postoperative pain after orthopedic surgery
1) individuals with diseases of the digestive tract
2) individuals with a history of hypersensitivity or allergy to any component of the test drug preparation
3) individuals with a history of myocardial infarction or angina
4) other individuals judged by the attending physician to be inappropriate for this study.
200
1st name | |
Middle name | |
Last name | Gen Inoue |
Kitasato University
Orthopaedic Surgery
1-15-1, Kitasato, Minami-ku, Sagamihara, Kanagawa
042-778-8707
ginoue@kitasato-u.ac.jp
1st name | |
Middle name | |
Last name | Gen Inoue |
Kitasato University
Orthopaedic Surgery
1-15-1, Kitasato, Minami-ku, Sagamihara, Kanagawa
042-778-8707
ginoue@kitasato-u.ac.jp
Kitasato University
Kitasato University
Self funding
Japan
NO
北里大学病院(神奈川県)、北里大学東病院(神奈川県)
2014 | Year | 08 | Month | 18 | Day |
Published
There was no significant difference in the maximum and mean NRS scores on each day between loxoprofen and celecoxib, suggesting a comparable analgesic effect for these 2 NSAIDs. Greater improvement in the NRS score between preadministration (baseline) and 30 minutes or 2 hours after administration was obtained for loxoprofen.
Completed
2012 | Year | 09 | Month | 06 | Day |
2013 | Year | 05 | Month | 10 | Day |
2014 | Year | 09 | Month | 05 | Day |
2014 | Year | 11 | Month | 10 | Day |
2014 | Year | 12 | Month | 02 | Day |
2015 | Year | 07 | Month | 11 | Day |
2014 | Year | 08 | Month | 12 | Day |
2015 | Year | 07 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017247
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |