Unique ID issued by UMIN | UMIN000014063 |
---|---|
Receipt number | R000016373 |
Scientific Title | Effect of mosapride citrate on human gastric accommodation |
Date of disclosure of the study information | 2014/05/26 |
Last modified on | 2014/05/25 19:04:32 |
Effect of mosapride citrate on human gastric accommodation
Effect of Mosapride on gastric accommodation
Effect of mosapride citrate on human gastric accommodation
Effect of Mosapride on gastric accommodation
Japan |
Functional dyspepsia
Gastroenterology | Adult |
Others
NO
To evaluate the hypothesis that mosapride enhances gastric accommodation in normal individuals
Efficacy
We inserted a tube with a bag into human proximal stomach, and compared the bag volume before and after a meal.
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
2
Treatment
Medicine |
Each subject performs experiments after administration of mosapride citrate.
Each subject performs experiments after administration of placebo.
20 | years-old | <= |
60 | years-old | >= |
Male
Subjects are healthy male indivisuals. None of the subjects have symptoms or a history of gastrointestinal disease or drug allergies, nor do they take any medication.
Subjects who have symptoms or a history of gastrointestinal disease or drug allergies, or who take any medication are excluded.
14
1st name | |
Middle name | |
Last name | Tomofumi Amano |
National center of Neurology and Psychiatry
General medicine
4-1-1 Ogawa-Higashi, Kodaira, Tokyo
042-341-2711
tamano@ncnp.go.jp
1st name | |
Middle name | |
Last name | Tomofumi Amano |
national center of Neurology and Psychiatry
General medicine
4-1-1 Ogawa-Higashi, Kodaira, Tokyo
042-341-2711
tamano@ncnp.go.jp
National center of Neurology and Psychiatry
National center of Neurology and Psychiatry
Other
Japan
NO
国立精神・神経医療研究センター
2014 | Year | 05 | Month | 26 | Day |
Unpublished
Gastric accommodation, expressed as the difference between pre and postmeal intra-bag volumes, was significantly enhanced by mosapride (322.5 +- 29.6 mL) compared with placebo (150.8 +- 26.2 mL, P=0.0004)
Completed
2011 | Year | 11 | Month | 08 | Day |
2011 | Year | 11 | Month | 08 | Day |
2014 | Year | 03 | Month | 31 | Day |
2014 | Year | 03 | Month | 31 | Day |
2014 | Year | 03 | Month | 31 | Day |
2014 | Year | 05 | Month | 25 | Day |
2014 | Year | 05 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000016373