Unique ID issued by UMIN | UMIN000013394 |
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Receipt number | R000015627 |
Scientific Title | The effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy |
Date of disclosure of the study information | 2014/03/11 |
Last modified on | 2018/09/13 09:42:25 |
The effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy
The effects of dexmedetomidine and fentanyl on emergence agitation in children
The effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy
The effects of dexmedetomidine and fentanyl on emergence agitation in children
Asia(except Japan) |
Adenotonsillectomy
Anesthesiology |
Others
NO
We aim to investigate the effects of dexmedetomidine and fentanyl on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy.
Efficacy
Confirmatory
Pragmatic
Not applicable
Emergence agitation score (using both a 5-point sacle and a PAED scale)
Hemodynamics including mean blood pressure and heart rate, recovery profiles including the time to restration of self-respiration, eye opening on verbal command, and extubation
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
3
Prevention
Medicine |
Control group will be infused with normal saline 10 ml throughout 10 min 6 min before anesthesia induction.
Dexmedetomidine group will be infused with dexmedetomidine 2 mcg/kg + normal saline (total 10 ml) throughout 10 min 6 min before anesthesia induction.
Fentanyl group will be infused with fentanyl 2 mcg/kg + normal saline (total 10 ml) throughout 10 min 6 min before anesthesia induction.
3 | years-old | <= |
10 | years-old | >= |
Male and Female
Pediatric patients aged 3~10 years with a physical status of 1 (the American Society of Anesthesiologists rating) who are scheduled to undergo elective adenotonsillectomy.
Patients with a history of cardiovascular, respiratory (asthma), neurologic (seizure), kidney, liver disease, mood disorder, prematurity, or developmental delay, the presence of upper respiratory infection, hypersensitivity to drugs, and those receiving analgesics, sedatives or psychiatric medication will be excluded.
90
1st name | |
Middle name | |
Last name | Byung Gun Lim |
Korea University Guro Hospital, Korea University College of Medicine
Department of Anesthesiology and Pain Medicine
148 Gurodong-ro, Guro-gu, Seoul, Korea
82-2-2626-1437
bglim9205@korea.ac.kr
1st name | |
Middle name | |
Last name | Byung Gun Lim |
Korea University Guro Hospital, Korea University College of Medicine
Department of Anesthesiology and Pain Medicine
148 Gurodong-ro, Guro-gu, Seoul, Korea
82-2-2626-1437
bglim9205@korea.ac.kr
Korea University
Korea University
Outside Japan
NO
Korea University Guro Hospital
2014 | Year | 03 | Month | 11 | Day |
Unpublished
Terminated
2014 | Year | 03 | Month | 03 | Day |
2014 | Year | 03 | Month | 12 | Day |
2014 | Year | 03 | Month | 11 | Day |
2018 | Year | 09 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000015627
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