UMIN-CTR Clinical Trial

Basic information
Official scientific title of the study	Association study of genome for common disease, especially circulatory diseases, renal disases and hypertension.
Title of the study (Brief title)	Association study of genome for common disease.
Region	Japan

Condition
Condition	common diseases, especially circulatory diseases, renal diseases, and hypertension
Classification by specialty	Medicine in general Cardiology Pneumology Endocrinology and Metabolism Nephrology
Classification by malignancy	Others
Genomic information	YES

Objectives
Narrative objectives1	To identify the susceptibility genes to common diseases, especially circulatory diseases, renal diseases, and hypertension
Basic objectives2	Others
Basic objectives -Others	Genetic search
Trial characteristics_1	Exploratory
Trial characteristics_2
Developmental phase

Assessment
Primary outcomes	allele freiquencies of genes
Key secondary outcomes	clinical test data blood pressure measurements

Base
Study type	Interventional

Study design
Basic design	Parallel
Randomization	Non-randomized
Randomization unit
Blinding	Open -no one is blinded
Control	No treatment
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms	2
Purpose of intervention	Prevention
Type of intervention	Gene
Interventions/Control_1	collecting blood for patients with common diseases, and extracting DNA.
Interventions/Control_2	collecting blood for healty volunteers
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

Eligibility
Age-lower limit	20 years-old <=
Age-upper limit	Not applicable
Gender	Male and Female
Key inclusion criteria	patients for common disease, especially circulatory diseases, renal diseases and hypertension
Key exclusion criteria	patients complicated with malignancy or mental diseases
Target sample size	1000

Research contact person
Name of lead principal investigator	Satoshi Umemura
Organization	Yokohama City University Graduate School of Medicine
Division name	Medical Science and Cardiorenal Medicine
Address	3-9 Fukuura, Kanazawa-ku, Yokohama City
TEL	045-787-2635
Email	umemuras@yokohama-cu.ac.jp

Public contact
Name of contact person	Keisuke Yatsu
Organization	Yokohama City University Graduate School of Medicine
Division name	Medical Science and Cardiorenal Medicine
Address	3-9 Fukuura, Kanazawa-ku, Yokohama City
TEL	045-787-2635
Homepage URL
Email	k-yatsu@be.wakwak.com

Sponsor
Institute	Yokohama City University Graduate School of Medicine
Institute
Department

Funding Source
Organization	self funding
Organization
Division
Category of Funding Organization	Self funding
Nationality of Funding Organization

Other related organizations
Co-sponsor
Name of secondary funｄer(s)

Secondary IDs
Secondary IDs	NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions

Other administrative information
Date of disclosure of the study information	2014 Year 01 Month 29 Day

Progress
Recruitment status	Completed
Date of protocol fixation	2013 Year 07 Month 25 Day
Anticipated trial start date	2014 Year 01 Month 29 Day
Last follow-up date	2018 Year 03 Month 31 Day
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Related information
URL releasing protocol
Publication of results	Unpublished
URL releasing results
Results
Other related information

Management information
Registered date	2014 Year 01 Month 29 Day
Last modified on	2017 Year 08 Month 02 Day

Link to view the page
URL(English)	https://upload.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000015177