Unique ID issued by UMIN | UMIN000011673 |
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Receipt number | R000013648 |
Scientific Title | The safety of novel gut peptide ghrelin for the treatment of chronic kidney disease |
Date of disclosure of the study information | 2013/09/10 |
Last modified on | 2013/09/06 19:04:18 |
The safety of novel gut peptide ghrelin for the treatment of chronic kidney disease
The safety ofghrelin
The safety of novel gut peptide ghrelin for the treatment of chronic kidney disease
The safety ofghrelin
Japan |
Chronic kidney disease
Medicine in general | Endocrinology and Metabolism | Nephrology |
Others
NO
To establish the novel therapeutic strategy against chronic kidney disease, we test the safety of administration of a novel gut peptide ghrelin.
Safety
Confirmatory
Pragmatic
Phase I
The temporal change of plasma concentration of ghrelin after the iv infusion
Change of eGFR
Anthropodic change
Renal function
Metabolic marker
Oxidative stressmarker
Nutrition status
Adverse effects by ghrelin infusion
Interventional
Single arm
Non-randomized
Single blind -participants are blinded
Uncontrolled
1
Treatment
Medicine |
ghrelin
20 | years-old | <= |
Not applicable |
Male and Female
1. Age over 20 years old
2. CKD patients at the stage, G3 and G4
3. BMI under 25
4. the patients that can cooperate with our study
1. subjects with severe liver dysfunction
2. subjects with neoplasma
3. subjects with severe infection
4. subjects with psychogenic disorder
5. sujects with allergic reaction to wheat, egg, and milk
6. pregnant women
7. subjects tha were not egligble for the stusy
6
1st name | |
Middle name | |
Last name | Hiroshi Itoh |
Keio University, Scool of Medicine
Division of nephrology, endocrinology, and metabolism
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
03-3353-1211
hiito@z8.keio.jp
1st name | |
Middle name | |
Last name | Shu Wakino |
Keio University, Scool of Medicine
Division of nephrology, endocrinology, and metabolism
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
03-3353-1211
shuwakino@z8.keio.jp
Keio University, Scool of Medicine, Division of nephrology, endocrinology, and metabolism
Ministry of Health, Labour and Welfare
Japan
NO
2013 | Year | 09 | Month | 10 | Day |
Unpublished
Preinitiation
2013 | Year | 07 | Month | 09 | Day |
2013 | Year | 09 | Month | 20 | Day |
2013 | Year | 09 | Month | 06 | Day |
2013 | Year | 09 | Month | 06 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013648
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