Unique ID issued by UMIN | UMIN000010816 |
---|---|
Receipt number | R000012662 |
Scientific Title | Efficacy of preoperative oral-rehydration therapy in preventing perioperative fluid overload and endothelial dysfunction |
Date of disclosure of the study information | 2013/06/01 |
Last modified on | 2014/09/08 11:26:18 |
Efficacy of preoperative oral-rehydration therapy in preventing perioperative fluid overload and endothelial dysfunction
Efficacy of preoperative oral-rehydration therapy in preventing perioperative fluid overload
Efficacy of preoperative oral-rehydration therapy in preventing perioperative fluid overload and endothelial dysfunction
Efficacy of preoperative oral-rehydration therapy in preventing perioperative fluid overload
Japan |
Adult planned surgical patients
Surgery in general | Gastrointestinal surgery | Anesthesiology |
Operative medicine | Adult |
Others
NO
To test the hypothesis that preoperative oral-rehydration therapy prevents perioperative excessive infusion and fluid accumulation by preserving endothelial and glycocalyx functions.
Efficacy
Confirmatory
Not applicable
Intraoperative Fluid Balance
Perioperative changes of body fluid measured with Bioelectrical impedance analysis
Plasma concentrations of endothelial and glycocaryx injury markers
Interventional
Parallel
Randomized
Individual
Single blind -investigator(s) and assessor(s) are blinded
No treatment
NO
Central registration
2
Treatment
Food |
Preoperative oral rehydration therapy
Preoperative fasting
20 | years-old | <= |
90 | years-old | > |
Male and Female
Patients scheduled for upper GI tract surgery (except for esophageal surgery) at Yokohama City University Hospital or Yokohama City University Medical Center, admitting to OR of which from 8:30 to 9:30 am
ASA class 3 and 4, GERD, History of upper GI surgery, Obstruction of GI tract, Obesity(>=BMI35), Anticipated airway difficulties, Emergency operations, 90years old and older, Arrythmia,implanted cardiac pacemakers, Preoperative parenteral infusion
50
1st name | |
Middle name | |
Last name | Kiyoyasu Kurahashi |
Yokohama City University
Department of Anesthesiology and Critical Care Medicine
3-9 Fukuura, Kanazawaku, Yokohamashi, Kanagawaken, Japan
1st name | |
Middle name | |
Last name |
Yokohama CIty University
Department of Anesthesiology and Critical Care Medicine
3-9 Fukuura, Kanazawaku, Yokohamashi, Kanagawaken, Japan
Department of Anesthesiology and Critical Care Medicine, Yokohama CIty University
none
Self funding
NO
2013 | Year | 06 | Month | 01 | Day |
Unpublished
Terminated
2013 | Year | 05 | Month | 10 | Day |
2013 | Year | 06 | Month | 01 | Day |
2013 | Year | 05 | Month | 28 | Day |
2014 | Year | 09 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000012662