Unique ID issued by UMIN | UMIN000010067 |
---|---|
Receipt number | R000011694 |
Scientific Title | GLP-1 administration test for assessing the glucose metabolism and predictive efficacy of the incretin based treatment |
Date of disclosure of the study information | 2013/04/01 |
Last modified on | 2017/08/03 17:04:58 |
GLP-1 administration test for assessing the glucose metabolism and predictive efficacy of the incretin based treatment
GLP-1 administration test
GLP-1 administration test for assessing the glucose metabolism and predictive efficacy of the incretin based treatment
GLP-1 administration test
Japan |
Type 2 diabetes mellitus
Endocrinology and Metabolism |
Others
NO
The purposes of this clinical trial are to assess the GLP-1 administration test reflects the insulin secretion capacity and predicts the efficacy of incretin based treatment.
Safety,Efficacy
1. Insulin secretion in GLP-1 administration compared to saline administration using meal tolerance test.
2. The relationship between the result of GLP-1 administration test and the changes of HbA1c after incretin based treatment.
Interventional
Cross-over
Non-randomized
Single blind -participants are blinded
Placebo
2
Prevention
Medicine |
GLP-1
saline
20 | years-old | <= |
75 | years-old | >= |
Male and Female
Diabetes mellitu type 2 without using incretin based drugs.
Patient with severe complication (proliferative retinopathy, serum cleatinine > 2.0 mg/dL, cerebrovascular disease, and/or ischemic heart diseases), severe liver dysfunction and/or dementia.
50
1st name | |
Middle name | |
Last name | Masamitsu Nakazato |
Miyazaki university, fuculty of medicine
Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine
5200 Kihara, Kiyotake, Miyazaki, Miyazaki, Japan
1st name | |
Middle name | |
Last name | Hiroaki Ueno |
Miyazaki university, fuculty of medicine
Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine
intron@med.miyazaki-u.ac.jp
Miyazaki university
None
Self funding
NO
2013 | Year | 04 | Month | 01 | Day |
Unpublished
Terminated
2012 | Year | 10 | Month | 12 | Day |
2013 | Year | 04 | Month | 01 | Day |
2017 | Year | 08 | Month | 03 | Day |
2017 | Year | 08 | Month | 03 | Day |
2017 | Year | 08 | Month | 03 | Day |
2013 | Year | 02 | Month | 18 | Day |
2017 | Year | 08 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011694