UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000008744 |
|---|---|
| Receipt number | R000010268 |
| Scientific Title | The frequency of transdifferentiation cells during the morphogenesis of Focal segmental glomerulosclerosis. |
| Date of disclosure of the study information | 2012/08/21 |
| Last modified on | 2012/08/21 17:54:01 |
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Basic information
Public title
The frequency of transdifferentiation cells during the morphogenesis of Focal segmental glomerulosclerosis.
Acronym
The frequency of transdifferentiation cells during the morphogenesis of Focal segmental glomerulosclerosis.
Scientific Title
The frequency of transdifferentiation cells during the morphogenesis of Focal segmental glomerulosclerosis.
Scientific Title:Acronym
The frequency of transdifferentiation cells during the morphogenesis of Focal segmental glomerulosclerosis.
Region
| Japan |
Condition
Condition
Focal segmental glomerulosclerosis
Classification by specialty
| Nephrology |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate the frequency of transdifferentiation of podocyte and parietal epithelial cell in FSGS.
Basic objectives2
Others
Basic objectives -Others
To clarify the pathophysiolosical mechanism of FSGS
Trial characteristics_1
Trial characteristics_2
Developmental phase
Not applicable
Assessment
Primary outcomes
Analyses of the histological frequency of transdifferentiating cell.
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Human kidney biopsy samples that were histologically diagnosed as focal segmental glomerulosclerosis.
Key exclusion criteria
None
Target sample size
30
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Michio Nagata |
Organization
Graduate School of Comprehensive Human Sciences, University of Tsukuba
Division name
Renal pathology
Zip code
Address
1-1-1, Ten-nodai, Tsukuba, Ibaraki, JAPAN
TEL
029-853-3938
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Michio Nagata |
Organization
University of Tsukuba
Division name
Renal pathology
Zip code
Address
1-1-1, Ten-nodai, Tsukuba, Ibaraki, JAPAN
TEL
029-853-3938
Homepage URL
nagatam@md.tsukuba.ac.jp
Sponsor or person
Institute
University of Tsukuba
Institute
Department
Personal name
Funding Source
Organization
None
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
None
Name of secondary funder(s)
None
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2012 | Year | 08 | Month | 21 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
No longer recruiting
Date of protocol fixation
| 2009 | Year | 04 | Month | 01 | Day |
Date of IRB
Anticipated trial start date
| 2009 | Year | 04 | Month | 01 | Day |
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
To evaluate the frequency of transdifferentiating cells in each variant of focal segmental glomerulosclerosis, and investigate how they contribute to the pathogenesis of this disease.
Management information
Registered date
| 2012 | Year | 08 | Month | 21 | Day |
Last modified on
| 2012 | Year | 08 | Month | 21 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000010268
