Unique ID issued by UMIN | UMIN000008844 |
---|---|
Receipt number | R000010208 |
Scientific Title | Evaluation of clinical guideline and establishment of evidence for the diagnosis and treatment of primary hyperaldosteronism in Japan. |
Date of disclosure of the study information | 2012/09/05 |
Last modified on | 2019/03/11 10:09:56 |
Evaluation of clinical guideline and establishment of evidence for the diagnosis and treatment of primary hyperaldosteronism in Japan.
PHAS-J3
Evaluation of clinical guideline and establishment of evidence for the diagnosis and treatment of primary hyperaldosteronism in Japan.
PHAS-J3
Japan |
Primary aldosteronism
Medicine in general | Cardiology | Endocrinology and Metabolism |
Nephrology | Neurology | Endocrine surgery |
Urology |
Others
NO
Adherence of clinical guideline and establishment of standard medication of primary adlosteronism
Safety,Efficacy
Confirmatory
Pragmatic
Phase IV
1)Adherance of clinical guideline for PA
2)Establishment of standard medication in PA and Aldosterone-rerated hypertension.
1)Implementation rate of each diagnostic procedure
2)Successful rate of the localization
3) Comparison of the effects of medical treatments and surgical treatment
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
Institution is considered as adjustment factor in dynamic allocation.
NO
Central registration
2
Treatment
Medicine |
Conventional antihypertensive agents with aldosterone antagonist
Conventional antihypertensive agents
20 | years-old | <= |
90 | years-old | >= |
Male and Female
Hypertensive patients in the outpatient clinics and hospitals, who full-fill the following 1) or 2) criteria:
1)treated hypertensive patients
2)untreated hypertensive patients with systolic blood pressure higher than 140mmHg or diastolic blood pressure higher than 90mmHg according to the guideline of the Japan Society of Hypertension
1)pregnant patients
2)patients taking aldosterone antagonist within the last one month
3)patients with the following diseases:
(1)secondary hypertension (renal hypertension,renovascular hypertension, primary aldosteronism, Cushing's syndrome, pheochromocytoma, etc)
(2)patients whom the attending doctors decides not suitable for the entry because of the unstable stage of the following complications: coronary diseases, arrhythmia, severe valvular diseases, cerebrovascular diseases, acute and chronic renal failure (serum Cr higher than 3mg/dl), acute and chronic liver diseases
4) Patients whom the attending doctor decides not suitable for the entry of the study.
2700
1st name | Mitsuhide |
Middle name | |
Last name | Naruse |
National Hospital Organization, Kyoto Medical Center
Clinical Research Institute for Endocrine and Metabolic Diseases
612-8555
1-1 Fukakusa-Mukaihatacho, Fushimiku, Kyoto, 612-8555, Japan
075-641-9161
yawata.rinshokenkyubu@gmail.com
1st name | Mitsuhide |
Middle name | |
Last name | Naruse |
National Hospital Organization, Kyoto Medical Center
Clinical Research Institute for Endocrine and Metabolic Diseases
6128555
1-1 Fukakusa-Mukaihatacho, Fushimiku, Kyoto, 612-8555, Japan
075-641-9161
yawata.rinshokenkyubu@gmail.com
National Hospital Organization
National Hospital Organization
Other
Japan
The Japan Endocrine Society
non
National Hospital Organization
5-21,2, higashigaoka, meguro-ku, Tokyo, Japan
03-5712-5075
kenkyu2004@nho.hosp.go.jp
NO
NHO函館病院(北海道)、NHO西群馬病院(群馬県)、NHO埼玉病院(埼玉県)、NHO金沢医療センター(石川県)、NHO名古屋医療センター(愛知県)、NHO三重病院(三重県)、NHO三重中央医療センター(三重県)、NHO京都医療センター(京都府)、NHO神戸医療センター(兵庫県)、NHO岡山医療センター(岡山県)、NHO呉医療センター・中国がんセンター(広島県)、NHO小倉医療センター(福岡県)、NHO九州医療センター(福岡県)、NHO長崎川棚医療センター(長崎県)、NHO熊本医療センター(熊本県)、佐世保市立総合病院(長崎県)、みさと健和病院(埼玉県)、岡崎市民病院(愛知県)、伊勢赤十字病院(三重県)
2012 | Year | 09 | Month | 05 | Day |
Unpublished
2641
Delay expected |
on analysis
Completed
2012 | Year | 07 | Month | 14 | Day |
2012 | Year | 09 | Month | 01 | Day |
2012 | Year | 09 | Month | 01 | Day |
2017 | Year | 09 | Month | 30 | Day |
2012 | Year | 09 | Month | 04 | Day |
2019 | Year | 03 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000010208