UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000008558 |
|---|---|
| Receipt number | R000010060 |
| Scientific Title | Differential gene expression analysis between tumor associated macrophages of alimental tract cancers and peripheral blood monocytes |
| Date of disclosure of the study information | 2012/12/01 |
| Last modified on | 2015/09/04 06:32:11 |
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Basic information
Public title
Differential gene expression analysis between tumor associated macrophages of alimental tract cancers and peripheral blood monocytes
Acronym
Analysis of specific gene expression profile of macrophages in alimental tract cancer tissues
Scientific Title
Differential gene expression analysis between tumor associated macrophages of alimental tract cancers and peripheral blood monocytes
Scientific Title:Acronym
Analysis of specific gene expression profile of macrophages in alimental tract cancer tissues
Region
| Japan |
Condition
Condition
Alimental tract cancer
Classification by specialty
| Gastroenterology | Gastrointestinal surgery |
Classification by malignancy
Malignancy
Genomic information
YES
Objectives
Narrative objectives1
To clarify the role of tumor infiltrationg macrophages in alimentaly tract cancers by comparing the gene expression profiles with peripheral blood monocytes of the same patients
Basic objectives2
Others
Basic objectives -Others
Analysis of specificity of cancer tissue
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Not applicable
Assessment
Primary outcomes
Extraction of genes specifically expressed in macrophages in alimentary tract cancer tissues in comparison with those in peripheral blood monocytes
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Patients of resectable alimentary tract cancers (esophageal cancer, gastric cancer and colorectal cancer) who come to Department of Gatroenterological Surgery, Kobe University Hospital
Key exclusion criteria
Patients who require pre-operative irradiation and/or chemotherapy
Target sample size
20
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Hiroshi Yokozaki |
Organization
Kobe University Graduate School of Medicine
Division name
Division of Pathology, Department of Pathology
Zip code
Address
7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo Prefecture
TEL
078-382-5460
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Hiroshi Yokozaki |
Organization
Kobe University Graduate School of Medicine
Division name
Division of Pathology, Department of Pathology
Zip code
Address
7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo Prefecture
TEL
078-382-5460
Homepage URL
hyoko@med.kobe-u.ac.jp
Sponsor or person
Institute
Kobe University Graduate School of Medicine
Institute
Department
Personal name
Funding Source
Organization
Japan Society for the Promotion of Science
Organization
Division
Category of Funding Organization
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
神戸大学大学院医学研究科（兵庫県） Kobe University Graduate School of Medicine (Hyogo)
Other administrative information
Date of disclosure of the study information
| 2012 | Year | 12 | Month | 01 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2012 | Year | 07 | Month | 24 | Day |
Date of IRB
Anticipated trial start date
| 2012 | Year | 12 | Month | 01 | Day |
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Before observation
Management information
Registered date
| 2012 | Year | 07 | Month | 29 | Day |
Last modified on
| 2015 | Year | 09 | Month | 04 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000010060
