Unique ID issued by UMIN | UMIN000008255 |
---|---|
Receipt number | R000009711 |
Scientific Title | The efficacy of combination therapy of cilostazol and acetaminophen |
Date of disclosure of the study information | 2012/06/26 |
Last modified on | 2013/06/27 12:12:00 |
The efficacy of combination therapy of cilostazol and acetaminophen
The efficacy of combination therapy of cilostazol and acetaminophen
The efficacy of combination therapy of cilostazol and acetaminophen
The efficacy of combination therapy of cilostazol and acetaminophen
Japan |
Ischemic stroke
Medicine in general | Cardiology | Neurology |
Others
NO
To compare the frequency of headaches caused by cilostazol in different ways of dosage in patients with ischemic stroke
Safety
Exploratory
Pragmatic
Not applicable
frequency of headache
Withdrawal of cilostazol due to adverse effect
Cardiovascular events
Pulse rate
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
NO
NO
YES
Numbered container method
2
Treatment
Medicine |
monotherapy Group : Cilostazol 200 mg/day
Combination group : Cilostazol 200 mg/day BID + acetaminophen 800mg/day BID for the first 7 days ,followed by Cilostazol 200 mg/day BID + acetaminophen 400mg/dayBID for two weeks, and then, use of acetaminophen as-needed at the time of onset of headache for three months.
Not applicable |
Not applicable |
Male and Female
1)inpatients with ischemic stroke detected by X-ray CT scan or MRI (non-cardioembolic)
2)both new-onset or recurrent ischemic stroke are permitted
1. Patients with hemorrhage or bleeding tendency.
2. Patients with congestive heart failure.
3. Patients with a history allergy against cilostazol or other antiplatelets.
4. Pregnant or possibly pregnant
5. Patients with severe hepatic or renal dysfunction
6. Patients who are judged inappropriate for the study by the investigators
100
1st name | |
Middle name | |
Last name | Ken Johkura |
Hiratsuka Kyosai Hospital
Department of Neurology
9-11 Oiwake, Hiratsuka, Kanagawa 254-8502, Japan
0463-32-1950
1st name | |
Middle name | |
Last name | Ryoo Yamamoto |
Hiratsuka Kyosai Hospital
Department of Neurology
9-11 Oiwake, Hiratsuka, Kanagawa 254-8502, Japan
0463-32-1950
ryamamoto-tuk@umin.ac.jp
Hiratsuka Kyosai Hospital
None
Self funding
NO
平塚共済病院 Hiratsuka Kyosai Hospital
2012 | Year | 06 | Month | 26 | Day |
Unpublished
Completed
2012 | Year | 06 | Month | 20 | Day |
2012 | Year | 06 | Month | 01 | Day |
2013 | Year | 05 | Month | 20 | Day |
2013 | Year | 05 | Month | 30 | Day |
2013 | Year | 05 | Month | 30 | Day |
2013 | Year | 12 | Month | 31 | Day |
2012 | Year | 06 | Month | 25 | Day |
2013 | Year | 06 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000009711