Unique ID issued by UMIN | UMIN000006368 |
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Receipt number | R000007558 |
Scientific Title | Epidemiological Assessment of NAFLD and Efficacy Evaluation of Nutritional and Exercise Intervention for NASH |
Date of disclosure of the study information | 2011/09/20 |
Last modified on | 2017/04/01 20:13:02 |
Epidemiological Assessment of NAFLD
and
Efficacy Evaluation of Nutritional and Exercise Intervention for NASH
Epidemiology of NAFLD and non-pharmacological intervention for NASH
Epidemiological Assessment of NAFLD
and
Efficacy Evaluation of Nutritional and Exercise Intervention for NASH
Epidemiology of NAFLD and non-pharmacological intervention for NASH
Japan |
Nonalcohol steatohepatitis
Medicine in general | Hepato-biliary-pancreatic medicine |
Others
NO
This study aims to clarify the morbidity of non-alcoholic fatty liver diseases and the efficacy of non-pharmaceutical intervention on non-alcoholic steatohepatitis.
Others
This study also focuses on the significance in NASH managements to measure shear wave velocity in the liver by implementing acoustic radiation force impulse, to define a stiffness of the carotid arterial wall, and to quantify APM2 gene products in the plasma.
Exploratory
Explanatory
Not applicable
A year after the first evaluation
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Treatment
Behavior,custom |
If a case desired, non-pharmaceutical intervention is planned in the first 30 cases, which showed an abnormal study in one or more of liver stiffness, rigidity of carotid artery or serum fibrosis markers. Nutritional counseling and exercise therapy are conducted once a month or 2-months.
No intervention
Not applicable |
Not applicable |
Male and Female
1. No medical history in terms of chronic liver damage.
2. All of AST, ALT and GTP show abnormal values.
3. None of positive reaction for HBsAg, anti-HCV, AMA or ANA.
4. It is possible to be followed for a year.
5. A written informed consent from a patient himself/herself.
For the people to start an exercise training
1. A pulse oximeter revealed oxygen saturation less than 95% at rest.
2. Abnormality in a 12-lead electrocardiogram at rest.
3. A doctor judged to be an improper case for this study.
30
1st name | |
Middle name | |
Last name | Takeshi Suda |
Niigata University Medical and Dental Hospital
Division of Gastroenterology & Hepatology
1-754 Asahi-machi, Chuo-ku, Niigata, Niigata 951-8122, Japan
025-227-2207
tspitt@med.niigta-u.ac.jp
1st name | |
Middle name | |
Last name | Kenya Kamimura |
Niigata University Graduate School of Medical and Dental Sciences
Division of Gastroenterology & Hepatology
1-754 Asahi-machi, Chuo-ku, Niigata, Niigata 951-8122, Japan
025-227-2207
tspitt@med.niigta-u.ac.jp
Niigata Hepatocellular Carcinoma Therapy Study Group
Non
Self funding
Japan
NO
1) 新潟大学大学院医歯学総合研究科 消化器内科学分野
2) 済生会新潟第二病院 消化器内科
3) 新潟市民病院 消化器内科
4) 新潟県労働衛生医学協会
2011 | Year | 09 | Month | 20 | Day |
Unpublished
Completed
2011 | Year | 09 | Month | 20 | Day |
2011 | Year | 10 | Month | 01 | Day |
2015 | Year | 03 | Month | 01 | Day |
2015 | Year | 09 | Month | 01 | Day |
2016 | Year | 03 | Month | 01 | Day |
2016 | Year | 03 | Month | 01 | Day |
2011 | Year | 09 | Month | 18 | Day |
2017 | Year | 04 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007558
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