Unique ID issued by UMIN | UMIN000004099 |
---|---|
Receipt number | R000004923 |
Scientific Title | Comparison of Adaptive Servo Ventilation(Bipap Auto SV Advanced) and Oxgen Therapy in Chronic Heart Failure Patients Complicated With Central Sleep Apnea. |
Date of disclosure of the study information | 2010/09/15 |
Last modified on | 2014/07/30 20:53:28 |
Comparison of Adaptive Servo Ventilation(Bipap Auto SV Advanced) and Oxgen Therapy in Chronic Heart Failure Patients Complicated With Central Sleep Apnea.
The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients
Comparison of Adaptive Servo Ventilation(Bipap Auto SV Advanced) and Oxgen Therapy in Chronic Heart Failure Patients Complicated With Central Sleep Apnea.
The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients
Japan |
Chronic Heart Failure
Sleep Apnea
Cardiology | Pneumology |
Others
NO
The aim of this study is to compare the effects of Adaptive Servo Ventilation(Bipap auto SV Advanced) and oxygen therapy in chronic heart failure patients complicated with central sleep apnea.
Efficacy
Left ventricular ejection fraction confirmed by echocardiography
Sleep quality
Endothelial function
Sleepiness and health-related QOL
Clinical measurements
Serum and urinary biomarkers
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Device,equipment |
Adaptive servo ventilation
(Bipap auto SV Advanced)
Nocturnal oxygen therapy
20 | years-old | <= |
80 | years-old | >= |
Male and Female
1.Left ventricular ejection fraction<50% confirmed by echocardiography
2.Apnea hypopnea index(AHI)>=20 confirmed by overnight polysomnography
3.More than 15% of AHI is due to CSA
1.Changes of cardioactive drug prescriptions within 6 weeks
2.Admission due to cardiovascular events within 6 weeks
3.Ever used CPAP or ASV for sleep apnea
4.Ever used nocturnal oxgen therapy
5.Subjects with acute exacerbation of chronic heart failure
6.Operation for upper airway within 90 days
35
1st name | |
Middle name | |
Last name | Michiaki Mishima |
Kyoto University, Graduate School of Medicine
Respiratory Medicine
54 Shogoin-Kawaracho Sakyo Kyoto
81-75-751-3852
mishima@kuhp.kyoto-u.ac.jp
1st name | |
Middle name | |
Last name | Kazuo Chin |
Kyoto University, Graduate School of Medicine
Respiratory Care and Sleep Control Medicine
54 Shogoin-Kawaracho Sakyo Kyoto
81-75-751-3852
chink@kuhp.kyoto-u.ac.jp
Kyoto University, Graduate School of Medicine
Philips Respironics
Profit organization
Kyoto University, Graduate School of Medicine,Cardiovascular Medicine
YES
NCT01187823
ClinicalTrials.gov
C-447
Ethics Committee of Kyoto University
京都大学医学部附属病院(京都府)
2010 | Year | 09 | Month | 15 | Day |
Unpublished
Completed
2010 | Year | 09 | Month | 15 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 08 | Month | 25 | Day |
2014 | Year | 07 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004923