Unique ID issued by UMIN | UMIN000004461 |
---|---|
Receipt number | R000004862 |
Scientific Title | CKD Research of Outcomes in Treatment and Epidemiology |
Date of disclosure of the study information | 2010/10/27 |
Last modified on | 2017/12/27 12:08:07 |
CKD Research of Outcomes in Treatment and Epidemiology
CKD-ROUTE Study
CKD Research of Outcomes in Treatment and Epidemiology
CKD-ROUTE Study
Japan |
Chronic kidney disease
Medicine in general | Nephrology |
Others
NO
This survey evaluates the relationship of endpoints to patient characteristics, complications and treatment and examines risk factors for CKD progression and poor prognosis to contribute development of appropriate therapy for CKD.
Others
A prospective cohort study
Exploratory
Not applicable
Decline in renal function defined by reduction in estimated GFR
Cardiovascular events
Renal replacement therapy
Death from cardiovascular events
Death from any cause without accident
Fractures (Fractures associated with major trauma, such as motor vehicle accidents are excluded.)
Hospitalization
Changes in the levels of WBC, Hb , Plt, TP, Alb, BUN, Cr, Na, K, Cl, Ca, P, Alp, T-Chol, TG, HDL, CK, Glu, HbA1c, Fe, UIBC (or TIBC), ferritin, CRP, intact PTH.
Changes in the levels of urinary protein and urinary blood
Changes in blood pressure
Changes in the values of body weight and BMI
Observational
20 | years-old | <= |
Not applicable |
Male and Female
All new patients with non-dialysis CKD (stage 2, 3, 4 and 5) at the participating nephrology departments, who will likely to be followed by nephrologists for at least 1 year, and who provide written informed consent to participate in the present survey.
Cancer
History of organ transplantation
Active gastrointestinal bleeding
1000
1st name | |
Middle name | |
Last name | Sei Sasaki |
Tokyo Medical and Dental University
Department of Nephrology
1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519 Japan
03-5803-5214
ssasaki.kid@tmd.ac.jp
1st name | |
Middle name | |
Last name | Yumi Noda |
Tokyo Medical and Dental University
Department of Chronic Kidney Disease
1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519 Japan
03-5803-5214
ynodmed2@tmd.ac.jp
Department of Nephrology, Tokyo Medical and Dental University
None
Self funding
Hospitals cooperated with Department of Nephrology, Tokyo Medical and Dental University
NO
東京医科歯科大学医学部付属病院腎臓内科および下記関連施設
取手協同病院、秀和綜合病院、中野総合病院、都立多摩総合医療センター、都立墨東病院、横須賀共済病院、都立大塚病院、武蔵野赤十字病院、平塚共済病院、東京共済病院、土浦協同病院、都立広尾病院、青梅市立総合病院、豊島病院、千葉東病院
2010 | Year | 10 | Month | 27 | Day |
Published
Iimori S, Noda Y, Okado T, Naito S, Toda T, et al. Baseline characteristics and prevalence of cardiovascular disease in newly visiting or referred chronic kidney disease patients to nephrology centers in Japan: a prospective cohort study. BMC Nephrol. 17;14:152, 2013.
Iimori S, Naito S, Noda Y, Nishida H, Kihira H, et al. Anaemia management and mortality risk in newly visiting patients with chronic kidney disease in Japan: The CKD-ROUTE study. Nephrology. 20:601-608, 2015.
Kikuchi H, Kanda E, Mandai S, Akazawa M, Iimori S, et al. Combination of low body mass index and serum albumin level is associated with chronic kidney disease progression: the chronic kidney disease-research of outcomes in treatment and epidemiology (CKD-ROUTE) study. Clin Exp Nephrol. 21:55-62, 2016.
Mandai S, Kanda E, Iimori S, Naito S, Noda Y, et al. Association of serum chloride level with mortality and cardiovascular events in chronic kidney disease: the CKD-ROUTE study. Clin Exp Nephrol. 21:104-111, 2017.
Arai Y, Kanda E, Iimori S, Naito S, Noda Y, et al. The use of vitamin D analogs is independently associated with the favorable renal prognosis in chronic kidney disease stages 4-5: the CKD-ROUTE study. Clin. Exp. Nephrol. 21:481-487, 2017.
Arai Y, Kanda E, Iimori S, Naito S, Noda Y, et al. Low white blood cell count is independently associated with chronic kidney disease progression in the elderly: the CKD-ROUTE study. Clin. Exp. Nephrol. 2017.
Iimori S, Naito S, Noda N, Sato H, Nomura N, et al. Prognosis of chronic kidney disease with normal-range proteinuria: The CKD-ROUTE study. PLoS One 2018.
Main results already published
2010 | Year | 10 | Month | 26 | Day |
2010 | Year | 11 | Month | 01 | Day |
2015 | Year | 01 | Month | 31 | Day |
2015 | Year | 07 | Month | 31 | Day |
2015 | Year | 07 | Month | 31 | Day |
A prospective cohort study
2010 | Year | 10 | Month | 27 | Day |
2017 | Year | 12 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004862