Unique ID issued by UMIN | UMIN000002490 |
---|---|
Receipt number | R000003053 |
Scientific Title | Pharmacogenetic analysis to investigate the association between efficacy and neurotoxicity of oxaliplatin and single nucleotide polymorphisms |
Date of disclosure of the study information | 2009/11/10 |
Last modified on | 2011/09/14 09:20:54 |
Pharmacogenetic analysis to investigate the association between efficacy and neurotoxicity of oxaliplatin and single nucleotide polymorphisms
Pharmacogenetic analysis of oxaliplatin
Pharmacogenetic analysis to investigate the association between efficacy and neurotoxicity of oxaliplatin and single nucleotide polymorphisms
Pharmacogenetic analysis of oxaliplatin
Japan |
Colorectal cancer
Gastroenterology | Hematology and clinical oncology | Gastrointestinal surgery |
Malignancy
YES
To investigate the association between the efficacy of oxaliplatin for liver metastasis and SNP of ERCC1-118 in colorectal cancer patients.
Others
To investigate the association between the oxaliplatin-induced neurotoxicity and SNP of GSTP1-105.
Confirmatory
Explanatory
Not applicable
To investigate the association between the efficacy of oxaliplatin for liver metastasis and SNP of ERCC1-118 in colorectal cancer patients.
To investigate the association between the oxaliplatin-induced neurotoxicity and SNP of GSTP1-105.
Observational
Not applicable |
Not applicable |
Male and Female
1. Histologically confirmed colorectal cancer patients with measurable liver metastasis who received oxaliplatin-based chemotherapy as first line treatment
2. Written informed consent is provided
The patients with a history of adjuvant chemotherapy using oxaliplatin
133
1st name | |
Middle name | |
Last name | Masashi Kanai |
Kyoto University Hospital
Outpatient Oncology Unit
54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan
1st name | |
Middle name | |
Last name |
Kyoto University Hospital
Outpatient Oncology Unit
075-751-4770
Kyoto University Hospital
Japanese Society for the promotion of Science
NO
京都大学医学部附属病院
2009 | Year | 11 | Month | 10 | Day |
Unpublished
Enrolling by invitation
2009 | Year | 09 | Month | 14 | Day |
2009 | Year | 11 | Month | 01 | Day |
2014 | Year | 10 | Month | 01 | Day |
Pharmacogenetic analysis of oxaliplatin
2009 | Year | 09 | Month | 14 | Day |
2011 | Year | 09 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003053