Unique ID issued by UMIN | UMIN000002342 |
---|---|
Receipt number | R000002869 |
Scientific Title | Effect of a group-based lifestyle intervention on risk factors and insulin resistance for metabolic syndrome |
Date of disclosure of the study information | 2009/09/01 |
Last modified on | 2009/08/17 13:48:09 |
Effect of a group-based lifestyle intervention on risk factors and insulin resistance for metabolic syndrome
Tabaruzaka study
Effect of a group-based lifestyle intervention on risk factors and insulin resistance for metabolic syndrome
Tabaruzaka study
Japan |
Metabolic syndrome
Endocrinology and Metabolism |
Others
NO
To evaluate the efficacy and sustained effects of two kind of group-based lifestyle interventions for the metabolic syndrome and the relationship between intervention effects and improvement of insulin sensitivity.
Efficacy
Confirmatory
Pragmatic
Not applicable
The effect of components of MS and insulin sensitivity after 10 months and further after 2 years of intervention.
The effect of BMI, blood pressure, lipid, blood glucose after 10 months and further after 2 years of intervention.
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
3
Prevention
Behavior,custom |
standard (S: 4-month intervention)
intensive intervention (I: 10-month intervention)
control group.
30 | years-old | <= |
69 | years-old | >= |
Male and Female
people who have at least one or more of the following criteria: obesity (BMI => 25); elevated BP (130 <= SBP < 160 mmHg or 85 <= DBP < 100 mmHg); dyslipidemia (LDL- C => 140 mg/dl, Triglyceride (TG) => 150 mg/dl or HDL-C < 40 mg/dl for male or HDL-C < 50 mg/dl for female); and impaired glucose homeostasis (110 <= FBS < 126 mg/dl, 140 <= BS at 120 min of 75g oral glucose tolerance test (75gOGTT) < 200 mg/dl, or 5.5 <= A1c < 6.1 %)
The subjects who take medication for hypertension, dyslipidemia and diabetes.
150
1st name | |
Middle name | |
Last name | Eiichi Araki |
Faculty of medical and pharmaceutical sciences, Kumamoto University.
Metabolic medicine
1-1-1, Honjo, Kumamoto, 860-8556, Japan.
+81-96-373-5169
1st name | |
Middle name | |
Last name | Takeshi Nishikawa |
Faculty of medical and pharmaceutical sciences, Kumamoto University.
Metabolic medicine
1-1-1, Honjo, Kumamoto, 860-8556, Japan.
+81-96-373-5169
takeshi@kumamoto-u.ac.jp
Metabolic medicine, Faculty of medical and pharmaceutical sciences, Kumamoto University.
Kokuho health-up model
Japan
Department of Preventive and Environmental Medicine Kumamoto University.
Metabolic medicine, Faculty of medical and pharmaceutical sciences, Kumamoto University.
NO
2009 | Year | 09 | Month | 01 | Day |
Published
After 10 months, Standard(S) and Intensive(I) intervention showed improvements of BMI , HDL-C, FBS, A1c and mean number of components of MS. Further after 2 years, sustained effect on BMI was observed in S and I. No change in mean number of components of MS from baseline in S and I and a significant increase in that of Control group were observed. An insulin sensitivity index and a hepatic insulin resistance index were improved after intervention. The improvements of components of MS were correlated with the increase in WBISI.
Completed
2003 | Year | 08 | Month | 01 | Day |
2003 | Year | 08 | Month | 01 | Day |
2006 | Year | 09 | Month | 01 | Day |
2006 | Year | 09 | Month | 01 | Day |
2006 | Year | 09 | Month | 01 | Day |
2009 | Year | 09 | Month | 01 | Day |
2009 | Year | 08 | Month | 17 | Day |
2009 | Year | 08 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002869