Unique ID issued by UMIN | UMIN000001800 |
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Receipt number | R000002171 |
Scientific Title | Phase II study of irinotecan and tegafur gimeracil for NSCLC with EGFR mutation which resistant to EGFR-TKI |
Date of disclosure of the study information | 2010/08/31 |
Last modified on | 2013/03/25 09:48:09 |
Phase II study of irinotecan and tegafur gimeracil for NSCLC with EGFR mutation which resistant to EGFR-TKI
TS-1+CPT for EGFR-TKI resistant EGFR Mt
Phase II study of irinotecan and tegafur gimeracil for NSCLC with EGFR mutation which resistant to EGFR-TKI
TS-1+CPT for EGFR-TKI resistant EGFR Mt
Japan |
Non-small-cell lung cancer
Pneumology | Hematology and clinical oncology |
Malignancy
NO
To evaluate the efficacy of TS-1+irinotecan combination for NSCLC with EGFR mutation which resistant to EGFR-TKI
Safety,Efficacy
Disease controll rate at 8 weeks after the initiation of treatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
tegafur gimeracil and irinotecan
Not applicable |
Not applicable |
Male and Female
1. Histlogically proven advanced non-small-cell lung cancer with EGFR mutation
2. Already treated with platinum-doublet and having resistance to EGFR-TKI
3. Having performance status 0-1
4. Having mesurable lesion
5. Having adequate organ functions
6. With written informed concent
1. Pre-treated with 5-FU related drugs or irinotecan
2. With severe comorbidities
3. With symptomatic brain metastasis
4. Pregnant women
25
1st name | |
Middle name | |
Last name | Shunichi Sugawara |
Sendai Kosei Hospital
Respiratory medicine
4-15, Hirose-machi, Aobaku, Sendai
1st name | |
Middle name | |
Last name |
North Japan Lung Cancer Study Group
Registration office
akinoue@idac.tohoku.ac.jp
North Japan Lung Cancer Study Group
North Japan Lung Cancer Study Group
Self funding
NO
2010 | Year | 08 | Month | 31 | Day |
Unpublished
Completed
2008 | Year | 11 | Month | 22 | Day |
2008 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2009 | Year | 03 | Month | 25 | Day |
2013 | Year | 03 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002171
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Research case data | |
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