Unique ID issued by UMIN | UMIN000001461 |
---|---|
Receipt number | R000001777 |
Scientific Title | Cardiac surgery in patients on dialysis: effectiveness of continuous infusion of low-dose human atrial natriuretic peptide |
Date of disclosure of the study information | 2008/10/29 |
Last modified on | 2014/10/29 09:28:09 |
Cardiac surgery in patients on dialysis: effectiveness of continuous infusion of low-dose human atrial natriuretic peptide
NU-HIT trial for HD
Cardiac surgery in patients on dialysis: effectiveness of continuous infusion of low-dose human atrial natriuretic peptide
NU-HIT trial for HD
Japan |
myocardial infarction, angina, valvular disease, thoracic aortic aneurysm
Cardiovascular surgery |
Others
NO
The risk of cardiac surgery in dialysis-dependent patients is high. We conducted the effect of hANP infusion for dialysis-dependent patients.
Efficacy
Confirmatory
Pragmatic
Phase II
mortality, MACCE
survival rate, complication,urine volume, BNP, ANP, renin activity, angiotensin II, aldosterone, blood urea nitrogen BUN, Cr
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
2
Treatment
Medicine |
Perioperative administration of hANP
Perioperative non-administration of hANP
20 | years-old | <= |
80 | years-old | > |
Male and Female
Dialysis dependent patient undergoing cardiac surgery
Patients from whom informed consent was obtained
cardiogenic shock
120
1st name | |
Middle name | |
Last name | Akira Sezai |
Nihon University School of Medicine
Department of Cardiovascular Surgery
30-1 Oyaguchi kami-machi, Itabashi-ku, Tokyo, Japan
03-3972-8111
asezai.med@gmail.com
1st name | |
Middle name | |
Last name | Akira Sezai |
Nihon University School of Medicine
Department of Cardiovascular Surgery
30-1 Oyaguchi kami-machi, Itabashi-ku, Tokyo, Japan
03-3972-8111
asezai.med@gmail.com
Nihon University School of Medicine
self funding
Self funding
a grant for the 60th anniversary of the Alumni Association of Nihon University School of Medicine and for the 50th anniversary of the foundation of Nihon University School of Medicine.
NO
2008 | Year | 10 | Month | 29 | Day |
Unpublished
Completed
1997 | Year | 03 | Month | 10 | Day |
1997 | Year | 03 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2008 | Year | 10 | Month | 29 | Day |
2014 | Year | 10 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001777