UMIN試験ID | UMIN000039055 |
---|---|
受付番号 | R000044540 |
科学的試験名 | フレイルが根治的膀胱全摘徐術の尿路変向選択に与える影響(FRAUD試験) |
一般公開日(本登録希望日) | 2020/01/08 |
最終更新日 | 2022/12/06 08:52:56 |
日本語
フレイルが根治的膀胱全摘徐術の尿路変向選択に与える影響(FRAUD試験)
英語
An observational study of the effect of frailty on the selection of a type of urinary diversion in patients with muscle-invasive bladder cancer: FRAUD study
日本語
フレイルが根治的膀胱全摘徐術の尿路変向選択に与える影響(FRAUD試験)
英語
An observational study of the effect of frailty on the selection of a type of urinary diversion in patients with muscle-invasive bladder cancer: FRAUD study
日本語
フレイルが根治的膀胱全摘徐術の尿路変向選択に与える影響(FRAUD試験)
英語
An observational study of the effect of frailty on the selection of a type of urinary diversion in patients with muscle-invasive bladder cancer: FRAUD study
日本語
フレイルが根治的膀胱全摘徐術の尿路変向選択に与える影響(FRAUD試験)
英語
An observational study of the effect of frailty on the selection of a type of urinary diversion in patients with muscle-invasive bladder cancer: FRAUD study
日本/Japan |
日本語
膀胱癌
英語
Urinary bladder cancer
泌尿器科学/Urology |
悪性腫瘍/Malignancy
いいえ/NO
日本語
To investigate the association of the frailty with urinary diversion after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC).
英語
To investigate the association of the frailty with urinary diversion after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC).
有効性/Efficacy
日本語
英語
日本語
The primary purpose was the effect of frailty on urinary diversion selection after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC).
英語
The primary purpose was the effect of frailty on urinary diversion selection after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC).
日本語
Secondary purposes included the association of frailty on complications and the effect of frailty on overall survival.
英語
Secondary purposes included the association of frailty on complications and the effect of frailty on overall survival.
観察/Observational
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
日本語
英語
20 | 歳/years-old | 以上/<= |
100 | 歳/years-old | 未満/> |
男女両方/Male and Female
日本語
Localized muscle-invasive bladder cancer patients who underwent radical cystectomy and urinary diversion
英語
Localized muscle-invasive bladder cancer patients who underwent radical cystectomy and urinary diversion
日本語
1) Localized muscle-invasive bladder cancer patients who do not undergo radical cystectomy and urinary diversion, and 2) who do not undergo frailty assessments.
英語
1) Localized muscle-invasive bladder cancer patients who do not undergo radical cystectomy and urinary diversion, and 2) who do not undergo frailty assessments.
100
日本語
名 | 真吾 |
ミドルネーム | |
姓 | 畠山 |
英語
名 | Shingo |
ミドルネーム | |
姓 | Hatakeyama |
日本語
弘前大学医学部
英語
Dept. of Urology, Hirosaki University Graduate School of Medicine
日本語
Urology
英語
Urology
036-8562
日本語
青森県弘前市在府町5
英語
5 Zaifu-chou, Hirosaki
0172395091
shingoh@hirosaki-u.ac.jp
日本語
名 | 畠山 |
ミドルネーム | |
姓 | 真吾 |
英語
名 | Shingo |
ミドルネーム | Hatakeyama |
姓 | Hatakeyama |
日本語
Dept. of Urology, Hirosaki University Graduate School of Medicine
英語
Dept. of Urology, Hirosaki University Graduate School of Medicine
日本語
泌尿器科
英語
Urology
036-8562
日本語
青森県弘前市在府町5
英語
5 Zaifu-chou, Hirosaki
0172395091
shingoh@hirosaki-u.ac.jp
日本語
弘前大学
英語
Dept. of Urology, Hirosaki University Graduate School of Medicine
日本語
日本語
日本語
英語
日本語
弘前大学
英語
Dept. of Urology, Hirosaki University Graduate School of Medicine
日本語
日本語
その他/Other
日本語
日本
英語
N/A = Not Applicable
日本語
英語
日本語
英語
日本語
Dept. of Urology, Hirosaki University Graduate School of Medicine
英語
Dept. of Urology, Hirosaki University Graduate School of Medicine
日本語
青森県弘前市在府町5
英語
Hirosaki
0172395091
rinri@hirosaki-u.ac.jp
いいえ/NO
日本語
英語
日本語
英語
2020 | 年 | 01 | 月 | 08 | 日 |
https://pubmed.ncbi.nlm.nih.gov/32452113/
最終結果が公表されている/Published
https://pubmed.ncbi.nlm.nih.gov/32452113/
88
日本語
Frailty is significantly associated with the type of urinary diversion, and it should be considered for the selection of urinary diversion in muscle-invasive bladder cancer patients undergoing radical cystectomy.
英語
Frailty is significantly associated with the type of urinary diversion, and it should be considered for the selection of urinary diversion in muscle-invasive bladder cancer patients undergoing radical cystectomy.
2022 | 年 | 12 | 月 | 06 | 日 |
日本語
英語
日本語
To investigate the effect of frailty on the type of urinary diversion after radical cystectomy in patients with muscle-invasive bladder cancer.
英語
To investigate the effect of frailty on the type of urinary diversion after radical cystectomy in patients with muscle-invasive bladder cancer.
日本語
Between January 2014 and January 2020, we prospectively evaluated frailty in 88 patients with localized muscle-invasive bladder cancer, who had received radical cystectomy and urinary diversion. The selection of the type of urinary diversion was determined by the operating surgeon based on performance status, comorbidities, tumor status and the patient's preference. The frailty evaluation included the Fried phenotype criteria, the modified frailty index and the frailty discriminant score.
英語
Between January 2014 and January 2020, we prospectively evaluated frailty in 88 patients with localized muscle-invasive bladder cancer, who had received radical cystectomy and urinary diversion. The selection of the type of urinary diversion was determined by the operating surgeon based on performance status, comorbidities, tumor status and the patient's preference. The frailty evaluation included the Fried phenotype criteria, the modified frailty index and the frailty discriminant score.
日本語
none
英語
none
日本語
We investigated the association between frailty and type of urinary diversion, the effect of frailty on postoperative complications and the effect of frailty on overall survival.
英語
We investigated the association between frailty and type of urinary diversion, the effect of frailty on postoperative complications and the effect of frailty on overall survival.
日本語
英語
日本語
英語
試験終了/Completed
2017 | 年 | 01 | 月 | 06 | 日 |
2017 | 年 | 01 | 月 | 06 | 日 |
2017 | 年 | 01 | 月 | 06 | 日 |
2022 | 年 | 12 | 月 | 05 | 日 |
日本語
This study is a retrospective analysis of our prospective observational study (UMIN000025057). We planned to assess the intra-group difference of frailty among the patients with prostate cancer (PC), renal cell carcinoma (RCC), and urothelial carcinoma (UC) after the development of the CGA tool.
In the UC cohort, we planned to evaluate 1) the intra-group difference of frailty among the different stages and treatments, the effect of frailty on safety and oncological outcomes 2) between the radical cystectomy and trimodal therapy in patients with MIBC (FRART-UC study), 3) between the neobladder and non-neobladder in patients with MIBC (FRAUD study), 4) in patients with upper tract urothelial carcinoma (FRAUT study), 5) metastatic urothelial carcinoma who underwent systemic chemotherapy and/or immunotherapy (FRAM-UC study), and 6) the association of baseline frailty and quality of life (FRAQ-UC study).
In the PC cohort, we planned to evaluate 1) the inter-group difference of frailty among the different stages and treatments (FRAPC study), the effect of frailty on safety and oncological outcomes 2) between the radical prostatectomy and radiation therapy in patients with localized prostate cancer (FRART-PC study), 3) among the patients with metastatic PC (FRAM-PC study), 4) the association of baseline frailty and quality of life (FRAQ-PC study), and 5) the association of baseline frailty and postoperative pain (FRAP study).
In the RCC cohort, we planned to evaluate 1) the inter-group difference of frailty among the different stages and treatments, the effect of frailty on safety and oncological outcomes 2) in the patients with radical or partial nephrectomy (FRARN study), 2) between in the mRCC patients with molecular targeted therapy and/or immunotherapy(FRARMT study), and 4) the association of baseline frailty and quality of life (FRAQ-RCC). Also, we planned to estimate the gap between chronological and biological age using frailty (FRAGE-GAP study).
英語
This study is a retrospective analysis of our prospective observational study (UMIN000025057). We planned to assess the intra-group difference of frailty among the patients with prostate cancer (PC), renal cell carcinoma (RCC), and urothelial carcinoma (UC) after the development of the CGA tool.
In the UC cohort, we planned to evaluate 1) the intra-group difference of frailty among the different stages and treatments, the effect of frailty on safety and oncological outcomes 2) between the radical cystectomy and trimodal therapy in patients with MIBC (FRART-UC study), 3) between the neobladder and non-neobladder in patients with MIBC (FRAUD study), 4) in patients with upper tract urothelial carcinoma (FRAUT study), 5) metastatic urothelial carcinoma who underwent systemic chemotherapy and/or immunotherapy (FRAM-UC study), and 6) the association of baseline frailty and quality of life (FRAQ-UC study).
In the PC cohort, we planned to evaluate 1) the inter-group difference of frailty among the different stages and treatments (FRAPC study), the effect of frailty on safety and oncological outcomes 2) between the radical prostatectomy and radiation therapy in patients with localized prostate cancer (FRART-PC study), 3) among the patients with metastatic PC (FRAM-PC study), 4) the association of baseline frailty and quality of life (FRAQ-PC study), and 5) the association of baseline frailty and postoperative pain (FRAP study).
In the RCC cohort, we planned to evaluate 1) the inter-group difference of frailty among the different stages and treatments, the effect of frailty on safety and oncological outcomes 2) in the patients with radical or partial nephrectomy (FRARN study), 2) between in the mRCC patients with molecular targeted therapy and/or immunotherapy(FRARMT study), and 4) the association of baseline frailty and quality of life (FRAQ-RCC). Also, we planned to estimate the gap between chronological and biological age using frailty (FRAGE-GAP study).
2020 | 年 | 01 | 月 | 05 | 日 |
2022 | 年 | 12 | 月 | 06 | 日 |
日本語
https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000044540
英語
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044540
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